By Barbara Zavan, Eriberto Bressan
This publication makes a speciality of the fundamental facets of dental stem cells (DSCs) in addition to their medical purposes in tissue engineering and regenerative drugs. It opens with a dialogue of type, protocols, and houses of DSCs and proceeds to discover DSCs in the contexts of cryopreservation; epigenetics; pulp, periodontal, enamel, bone, and corneal stroma regeneration; neuronal homes, mesenchymal stem cells and biomaterials; and as resources of hepatocytes for liver disorder remedy. The fifteen expertly authored chapters comprehensively research attainable purposes of DSCs and supply priceless insights into mechanisms of progress and differentiation.
Dental Stem Cells: Regenerative power attracts from a wealth of foreign views and is a necessary addition to the constructing literature on dental stem cells. This installment of Springer’s Stem phone Biology and Regenerative drugs sequence is integral for biomedical researchers attracted to bioengineering, dentistry, tissue engineering, regenerative drugs, mobile biology and oncology.
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Extra info for Dental Stem Cells: Regenerative Potential
Lindroos B, Mäenpää K, Ylikomi T et al (2008) Characterisation of human dental stem cells and buccal mucosa fibroblasts. Biochem Biophys Res Commun 368(2):329–335 34. D'Aquino R, Graziano A, Sampaolesi M et al (2007) Human postnatal dental pulp cells codifferentiate into osteoblasts and endotheliocytes: a pivotal synergy leading to adult bone tissue formation. Cell Death Differ 14(6):1162–1171 35. Gronthos S, Brahim J, Li W et al (2002) Stem cell properties of human dental pulp stem cells. J Dent Res 81(8):531–535 36.
It’s 42 J. Suchánek et al. harvest after tooth organ extraction is relatively easy as it is not firmly adjunct to the tooth. Due to this timing issue, the most frequent source of this tissue are the third molars extracted from the young donors (around 10–14 years old). These teeth are frequently extracted for orthodontic reasons and are commonly completely embedded in the jaw bone. Mature Tooth-Supportive Tissues Extraction Periodontal Ligament and Gingiva Extraction Periodontal ligament is specialized connective tissue localized between the alveolar bone and root surface, and is hidden under gingiva.
References 1. Miletich I, Sharpe PT (2004) Neural crest contribution to mammalian tooth formation. Birth Defects Res C Embryo Today 72(2):200–212 2. Zavan B, Bressan E, Sivolella S et al (2011) Dental pulp stem cells and tissue engineering strategies for clinical application on odontoiatric field. In: Pignatello R (ed) Biomaterials science and engineering, Intech. 5772/24871 3. Jimenez-Rojo L, Ibarretxe G, Aurrekoetxea M et al (2010) Epiprofin/Sp6: a new player in the regulation of tooth development.
Dental Stem Cells: Regenerative Potential by Barbara Zavan, Eriberto Bressan